孤立性空腹血糖受损患者中血管性血友病因子水平与平均血小板体积的关系。
The relationship between levels of von Willebrand factor and mean platelet volume in subjects with isolated impaired fasting glucose.
机构信息
Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey.
出版信息
Med Sci Monit. 2011 Jun;17(6):PR1-4. doi: 10.12659/msm.881786.
BACKGROUND
To understand the heterogeneity of platelets, we investigated the correlation between von Willebrand factor (vWf) and mean platelet volume (MPV) in subjects with isolated impaired fasting glucose (IFG).
MATERIAL/METHODS: We selected 48 subjects with isolated IFG and 48 normoglycemic control subjects matched for age, sex, and body mass index. We measured levels of vWf and MPV in all subjects.
RESULTS
The levels of vWf and MPV were significantly higher in the isolated IFG group than the control group (p<0.05) Also, vWf level was positively correlated with MPV level in subjects in the isolated IFG group (r=0.452, p=0.001).
CONCLUSIONS
Our results suggest that vWf seems to be profoundly related to platelet volume in subjects with isolated IFG.
背景
为了了解血小板的异质性，我们研究了孤立性空腹血糖受损（IFG）患者中血管性血友病因子（vWf）与平均血小板体积（MPV）之间的相关性。
材料/方法：我们选择了 48 例孤立性 IFG 患者和 48 例年龄、性别和体重指数匹配的血糖正常对照组。我们测量了所有受试者的 vWf 和 MPV 水平。
结果
孤立性 IFG 组的 vWf 和 MPV 水平明显高于对照组（p<0.05）。此外，孤立性 IFG 组中 vWf 水平与 MPV 水平呈正相关（r=0.452，p=0.001）。
结论
我们的结果表明，vWf 似乎与孤立性 IFG 患者的血小板体积有密切关系。
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