上呼吸道症状、肾脏受累及血管炎：一例韦格纳肉芽肿病病例报告及文献复习
Upper respiratory tract symptoms, renal involvement and vasculitis: a case report and review of wegener granulomatosis.
作者信息
Said Mohd Shahrir Mohamed
机构信息
University Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Cheras 56000 Kuala Lumpur, Malaysia. Email:
出版信息
J Clin Med Res. 2010 Aug 18;2(4):189-93. doi: 10.4021/jocmr412w.
Abstract
UNLABELLED
Wegeners Granulomatosis is a condition associated with systemic vasculitis which can present with upper respiratory tract symptoms initially. On September 2001, a 15-year-old girl presented with symptoms of nasal block for 3 weeks. She later developed joint pains and worsening renal status requiring dialysis. A renal biopsy was performed which showed pauci-immune cresentric glomerulonephritis. Her cANCA levels were positive. She was treated with oral cyclophosphamide and steroids and later responded.
KEYWORDS
Wegener granulomatosis; Young girl; Cyclophophamide; cANCA.
摘要
未标注
韦格纳肉芽肿病是一种与系统性血管炎相关的疾病，最初可表现为上呼吸道症状。2001年9月，一名15岁女孩出现鼻塞症状3周。随后她出现关节疼痛，肾功能恶化需要透析。进行了肾活检，显示为少免疫性新月体性肾小球肾炎。她的抗中性粒细胞胞浆抗体（cANCA）水平呈阳性。她接受了口服环磷酰胺和类固醇治疗，后来病情好转。
关键词
韦格纳肉芽肿病；年轻女孩；环磷酰胺；抗中性粒细胞胞浆抗体
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