Alpantaki Kalliopi, Datsis George, Zoras Odysseas, Kampouroglou Alkisti, Drositis Ioannis, Halkiadakis George, Katonis Pavlos
Departments of Orthopaedics and Traumatology, University Hospital of Heraklion, Voutes, Heraklion, 71003 Crete, Greece.
Case Rep Med. 2011;2011:243243. doi: 10.1155/2011/243243. Epub 2011 May 10.
Chondrosarcomas of the spine are rare and difficult to treat. In this paper a case of thoracic chondrosarcoma is presented. Chondrosarcomas of the spine are generally smaller, more difficult to excise and are followed by higher local recurrence compared with chondrosarcomas of the peripheral skeleton. The tumor is radio- and chemoresistant, making the surgical treatment of utmost importance. The most important prognostic factor for local control is wide or marginal tumor resection. Our patient was treated in two stages, with total excision of the tumor, using cryosurgery. Liquid nitrogen was used to freeze the damaged tissue at a cellular level and made the excision more efficient.
脊柱软骨肉瘤较为罕见且治疗困难。本文报告一例胸椎软骨肉瘤病例。与外周骨骼的软骨肉瘤相比,脊柱软骨肉瘤通常体积较小,更难切除,且局部复发率更高。该肿瘤对放疗和化疗均耐药,因此手术治疗至关重要。实现局部控制的最重要预后因素是广泛或边缘性肿瘤切除。我们的患者分两个阶段进行治疗,采用冷冻手术将肿瘤完整切除。使用液氮在细胞水平冷冻受损组织,使切除更有效。