七元环亚胺的合成及对映选择性氢化：取代的二苯并[b,f][1,4]噁嗪。
Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: substituted dibenzo[b,f][1,4]oxazepines.
机构信息
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, PR China.
出版信息
Chem Commun (Camb). 2011 Jul 21;47(27):7845-7. doi: 10.1039/c1cc12263k. Epub 2011 May 31.
PMID:21629945
Abstract
Highly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to 94% ee, by using the Ir(COD)Cl/(S)-Xyl-C(3)*-TunePhos complex as the catalyst in the presence of morpholine-HCl.
摘要
高对映选择性氢化七元环亚胺，取代的二苯并[b,f][1,4]氧氮杂卓，使用Ir(COD)Cl/(S)-Xyl-C(3)*-TunePhos 配合物作为催化剂，在吗啉盐酸盐存在下，可获得高达 94%的对映体过量值。
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