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高危手术的医院容量和手术死亡率趋势。

Trends in hospital volume and operative mortality for high-risk surgery.

机构信息

Center for Healthcare Outcomes and Policy and the Section of General Surgery, Department of Surgery, University of Michigan, Ann Arbor, USA.

出版信息

N Engl J Med. 2011 Jun 2;364(22):2128-37. doi: 10.1056/NEJMsa1010705.

Abstract

BACKGROUND

There were numerous efforts in the United States during the previous decade to concentrate selected surgical procedures in high-volume hospitals. It remains unknown whether referral patterns for high-risk surgery have changed as a result and how operative mortality has been affected.

METHODS

We used national Medicare data to study patients undergoing one of eight different cancer and cardiovascular operations from 1999 through 2008. For each procedure, we examined trends in hospital volume and market concentration, defined as the proportion of Medicare patients undergoing surgery in the top decile of hospitals by volume per year. We used regression-based techniques to assess the effects of volume and market concentration on mortality over time, adjusting for case mix.

RESULTS

Median hospital volumes of four cancer resections (lung, esophagus, pancreas, and bladder) and of repair of abdominal aortic aneurysm (AAA) rose substantially. Depending on the procedure, higher hospital volumes were attributable to an increasing number of cases nationwide, an increasing market concentration, or both. Hospital volumes rose slightly for aortic-valve replacement but fell for coronary-artery bypass grafting and carotid endarterectomy. Operative mortality declined for all eight procedures, ranging from a relative decline of 8% for carotid endarterectomy (1.3% mortality in 1999 and 1.2% in 2008) to 36% for AAA repair (4.4% in 1999 and 2.8% in 2008). Higher hospital volumes explained a large portion of the decline in mortality for pancreatectomy (67% of the decline), cystectomy (37%), and esophagectomy (32%), but not for the other procedures.

CONCLUSIONS

Operative mortality with high-risk surgery fell substantially during the previous decade. Although increased market concentration and hospital volume have contributed to declining mortality with some high-risk cancer operations, declines in mortality with other procedures are largely attributable to other factors. (Funded by the National Institute on Aging.).

摘要

背景

在过去的十年中,美国有许多努力致力于将某些外科手术集中在高容量医院进行。目前尚不清楚高风险手术的转诊模式是否因此发生了变化,以及手术死亡率受到了何种影响。

方法

我们使用国家医疗保险数据研究了 1999 年至 2008 年间进行的八种不同癌症和心血管手术的患者。对于每种手术,我们检查了医院容量和市场集中的趋势,定义为每年按容量排在前十分位数的医院中接受手术的医疗保险患者的比例。我们使用基于回归的技术来评估随着时间的推移,容量和市场集中对死亡率的影响,同时调整病例组合。

结果

四种癌症切除术(肺、食管、胰腺和膀胱)和腹主动脉瘤修复术(AAA)的中位医院容量大幅上升。根据手术的不同,更高的医院容量归因于全国范围内病例数量的增加、市场集中程度的提高或两者兼而有之。主动脉瓣置换术的医院容量略有上升,而冠状动脉旁路移植术和颈动脉内膜切除术的容量则下降。所有八种手术的手术死亡率均下降,从颈动脉内膜切除术的相对下降 8%(1999 年死亡率为 1.3%,2008 年为 1.2%)到 AAA 修复术的 36%(1999 年为 4.4%,2008 年为 2.8%)。对于胰腺癌切除术(67%的死亡率下降)、膀胱切除术(37%)和食管癌切除术(32%),医院容量的提高解释了死亡率下降的很大一部分,但对于其他手术则不然。

结论

过去十年中,高风险手术的手术死亡率大幅下降。尽管某些高风险癌症手术的死亡率下降与市场集中程度和医院容量的增加有关,但其他手术死亡率的下降主要归因于其他因素。(由美国国家老龄化研究所资助)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b3c/3150488/4b8655eb5552/nihms313480f1.jpg

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