前瞻性随机对照临床试验，研究肝切除术时使用的缝合类型。
Prospective randomized controlled trial investigating the type of sutures used during hepatectomy.
机构信息
Department of Surgery, Iizuka Hospital, Fukuoka 820-8505, Japan.
出版信息
World J Gastroenterol. 2011 May 14;17(18):2338-42. doi: 10.3748/wjg.v17.i18.2338.
AIM
To determine whether absorbable sutures or non-absorbable sutures are better in preventing surgical site infection (SSI), in this paper we discuss the results of a randomized clinical trial which examined the type of sutures used during hepatectomy.
METHODS
All hepatic resections performed from January 2007 to November 2008 at the Department of Surgery at Iizuka Hospital in Japan were included in this study. There were 125 patients randomly assigned to an absorbable sutures (Vicryl) group or non-absorbable sutures (Silk) group.
RESULTS
SSI was observed in 13.6% (17/125) patients participating in this study, 11.3% in the Vicryl group and 15.8% in the Silk group. Incisional SSI including superficial and deep SSI, was observed in 8% of the Vicryl group and 9.5% of the Silk group. Organ/space SSI was observed in 3.2% of the Vicryl group and 6.0% of the Silk group. There were no significant differences, but among the patients with SSI, the period for recovery was significantly shorter for the Vicryl group compared to the Silk group.
CONCLUSION
The incidence of SSI in patients receiving absorbable sutures and silk sutures is not significantly different in this randomized controlled study; however, the period for recovery in patients with SSI was significantly shorter for absorbable sutures.
目的
本研究旨在探讨肝切除术中使用缝线种类对预防手术部位感染（SSI）的影响，比较可吸收缝线与不可吸收缝线在预防 SSI 方面的效果。
方法
本研究纳入了 2007 年 1 月至 2008 年 11 月期间在日本饭冢医院外科行肝切除术的所有患者。将 125 例患者随机分为可吸收缝线（薇乔）组或不可吸收缝线（丝裂霉素）组。
结果
本研究中共有 13.6%（17/125）的患者发生 SSI，薇乔组为 11.3%，丝裂霉素组为 15.8%。薇乔组和丝裂霉素组的切口 SSI（包括浅表和深部 SSI）发生率分别为 8%和 9.5%，器官/腔隙 SSI 发生率分别为 3.2%和 6.0%。两组间差异无统计学意义，但 SSI 患者的恢复时间明显短于丝裂霉素组。
结论
在这项随机对照研究中，使用可吸收缝线和丝裂霉素缝线的患者 SSI 发生率无显著差异；然而，对于发生 SSI 的患者，可吸收缝线的恢复时间明显更短。
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