Dai W
Zhonghua Yi Xue Za Zhi. 1990 Mar;70(3):133-4, 12.
Forty-nine cases of gastric polyp (GP) were studied by histologic classification and immunohistochemical localization of monoclonal antibody MG 7 against gastric carcinoma. There were 12 cases (24.5%) of inflammatory polyp; 19 cases (38.8%) of hyperplastic polyp and 18 cases (36.7%) of adenomatous polyp. 3 cases (6.1%) of GP were malignant, among which 2 (11.1%) were adenomatous polyp and 1 (5.3%) was hyperplastic polyp. Seventeen cases (34.7%) of GP were MG 7 positive by ABC method, including 7 (36.8%) of hyperplastic polyp and 10 (55.5%) of adenomatous polyp. The inflammatory polyps were negative, and all of the cases with malignancy were strongly positive. The results showed that both GP and gastric carcinoma express MG 7 related antigen. These suggest that adenomatous polyp and hyperplastic polyp are closely related with gastric carcinogenesis.
对49例胃息肉（GP）进行了组织学分类及抗胃癌单克隆抗体MG 7的免疫组化定位研究。其中炎性息肉12例（24.5%）；增生性息肉19例（38.8%）；腺瘤性息肉18例（36.7%）。胃息肉恶变3例（6.1%），其中腺瘤性息肉2例（11.1%），增生性息肉1例（5.3%）。采用ABC法检测显示，17例（34.7%）胃息肉MG 7阳性，其中增生性息肉7例（36.8%），腺瘤性息肉10例（55.5%）。炎性息肉为阴性，所有恶变病例均呈强阳性。结果表明胃息肉与胃癌均表达MG 7相关抗原。提示腺瘤性息肉和增生性息肉与胃癌发生密切相关。
