Franquet Tomás
Jefe de la Sección de Radiología Torácica, Hospital de San Pablo, Profesor asociado de Radiología, Universidad Autónoma de Barcelona, Barcelona, España.
Arch Bronconeumol. 2011 Apr;47 Suppl 2:20-6. doi: 10.1016/S0300-2896(11)70017-5.
Imaging techniques are highly useful diagnostic tools to study small airway diseases. Despite their differences, from a clinical pathological perspective, these diseases show similar radiological manifestations. High-resolution computed tomography (CT) is the technique of choice to study diffuse diseases and those of the small airways; the slices obtained in expiratory high-resolution CT scan should form part of the study protocol of small airway diseases. Based on the findings of high-resolution CT, small airway diseases can be divided into two large groups: (a) those presenting direct morphological signs of bronchiolar involvement, and (b) those showing indirect signs of bronchiolar involvement (air trapping/mosaic pattern). High-resolution CT is highly useful to study the complications of asthma (allergic bronchopulmonary aspergillosis) and to evaluate clinically similar processes, such as hypersensitivity pneumonitis. In asthmatic patients, multi-detector CT (MDTC) allows clinical symptoms, thickening of the airway wall and the degree of airflow obstruction to be directly correlated. MDTC is also useful for quantitative evaluation of the degree of air trapping in patients with emphysema. Magnetic resonance imaging after inhalation of distinct gases, such as (3)He and xenon-129 and dual-energy CT are also useful imaging techniques in the direct or indirect evaluation of the degree of airflow obstruction (air trapping).
成像技术是研究小气道疾病非常有用的诊断工具。尽管这些疾病存在差异,但从临床病理学角度来看,它们具有相似的放射学表现。高分辨率计算机断层扫描(CT)是研究弥漫性疾病和小气道疾病的首选技术;呼气期高分辨率CT扫描获得的图像应成为小气道疾病研究方案的一部分。根据高分辨率CT的检查结果,小气道疾病可分为两大类:(a)呈现细支气管受累直接形态学征象的疾病,以及(b)显示细支气管受累间接征象(空气潴留/马赛克征)的疾病。高分辨率CT对于研究哮喘的并发症(变应性支气管肺曲霉病)以及评估临床类似的疾病过程(如过敏性肺炎)非常有用。在哮喘患者中,多排探测器CT(MDTC)可使临床症状、气道壁增厚与气流阻塞程度直接相关。MDTC对于定量评估肺气肿患者的空气潴留程度也很有用。吸入特定气体(如³He和氙-129)后的磁共振成像以及双能CT也是直接或间接评估气流阻塞程度(空气潴留)的有用成像技术。