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[患有和未患有心血管疾病患者中与高血压控制不佳相关的因素]

[Factors associated with uncontrolled hypertension in patients with and without cardiovascular disease].

作者信息

Cordero Alberto, Bertomeu-Martínez Vicente, Mazón Pilar, Fácila Lorenzo, Bertomeu-González Vicente, Cosín Juan, Galve Enrique, Núñez Julio, Lekuona Iñaki, González-Juanatey José R

机构信息

Departamento de Cardiología, Hospital Universitario de San Juan, 3550 Sant Joan d'Alacant, Alicante, Spain.

出版信息

Rev Esp Cardiol. 2011 Jul;64(7):587-93. doi: 10.1016/j.recesp.2011.03.008. Epub 2011 Jun 2.

Abstract

INTRODUCTION AND OBJECTIVES

Hypertension is one of the most prevalent and poorly controlled risk factors, especially in patients with established cardiovascular disease (CVD). The aim of this study was to describe the rate of blood pressure (BP) control and related risk factors.

METHODS

Multicenter, cross-sectional and observational registry of patients with hypertension recruited from cardiology and primary care outpatient clinics. Controlled BP defined as <140/90 mmHg.

RESULTS

55.4% of the 10 743 patients included had controlled BP and these had a slightly higher mean age. Patients with uncontrolled BP were more frequently male, with a higher prevalence of active smokers, obese patients, and patients with diabetes. The rate of controlled BP was similar in patients with or without CVD. Patients with uncontrolled BP had higher levels of blood glucose, total cholesterol, low density lipoproteins and uric acid. Patients with uncontrolled BP were receiving a slightly higher mean number of antihypertensive drugs compared to patients with controlled BP. Patients with CVD were more frequently receiving a renin-angiotensin-aldosterone axis inhibitor: 83.5% vs. 73.2% (P<.01). Multivariate analysis identified obesity and current smoking as independently associated with uncontrolled BP, both in patients with or without CVD, as well as relevant differences between the two groups on other factors.

CONCLUSIONS

Regardless of the presence of CVD, 55% of hypertensive patients had controlled BP. Lifestyle and diet, especially smoking and obesity, are independently associated with lack of BP control. Full English text available from: www.revespcardiol.org.

摘要

引言与目的

高血压是最常见且控制不佳的危险因素之一,尤其是在已确诊心血管疾病(CVD)的患者中。本研究的目的是描述血压(BP)控制率及相关危险因素。

方法

从心脏病学和初级保健门诊招募的高血压患者进行多中心、横断面观察性登记。血压控制定义为<140/90 mmHg。

结果

纳入的10743例患者中,55.4%的患者血压得到控制,且这些患者的平均年龄略高。血压未得到控制的患者男性更为常见,当前吸烟者、肥胖患者和糖尿病患者的患病率更高。有无CVD的患者血压控制率相似。血压未得到控制的患者血糖、总胆固醇、低密度脂蛋白和尿酸水平较高。与血压得到控制的患者相比,血压未得到控制的患者服用的抗高血压药物平均数量略多。患有CVD的患者更常接受肾素 - 血管紧张素 - 醛固酮轴抑制剂治疗:83.5%对73.2%(P<.01)。多变量分析确定肥胖和当前吸烟与血压未得到控制独立相关,无论患者有无CVD,以及两组在其他因素上的相关差异。

结论

无论是否存在CVD,55%的高血压患者血压得到了控制。生活方式和饮食,尤其是吸烟和肥胖,与血压控制不佳独立相关。完整英文文本可从:www.revespcardiol.org获取。

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