班加西（东利比亚）17 个 Y-STR 标记的群体遗传学数据。
Population genetic data for 17 Y STR markers from Benghazi (East Libya).
机构信息
School of Natural and Applied Sciences, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, UK.
出版信息
Forensic Sci Int Genet. 2012 Mar;6(2):224-7. doi: 10.1016/j.fsigen.2011.05.001. Epub 2011 Jun 2.
The seventeen Y-STR loci included in the AmpFℓSTR(®) Yfiler™ PCR Amplification kit (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438, DYS439, DYS437, DYS448, DYS458, DYS456, DYS635, and Y-GATA-H4) were used to type a sample population of 238 males from eastern Libya (Benghazi region). Of 238 observed haplotypes, 214 were unique (90%) and 24 (10%) were found more than once. The 17 loci gave a discriminating power of 0.999. DYS458 showed the highest diversity as a single-locus marker (0.73). Allelic frequencies and gene diversities for each Y-STR locus were determined. The high haplotype diversity and discrimination capacity (0.996) demonstrate the utility of these loci for human identification in forensic applications. Comparative analysis with Y-STR datasets of relevant populations and submission of the haplotypes to the Y-STR Haplotype Reference Database (YHRD) was undertaken.
十七个 Y-STR 基因座包括在 AmpFℓSTR(®) Yfiler™ PCR 扩增试剂盒（DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393、DYS385a/b、DYS438、DYS439、DYS437、DYS448、DYS458、DYS456、DYS635 和 Y-GATA-H4）用于对来自利比亚东部（班加西地区）的 238 名男性样本进行分型。在观察到的 238 个单倍型中，有 214 个是独特的（90%），有 24 个（10%）出现了不止一次。17 个基因座的鉴别力为 0.999。DYS458 作为单一基因座标记显示出最高的多样性（0.73）。确定了每个 Y-STR 基因座的等位基因频率和基因多样性。高单倍型多样性和鉴别能力（0.996）表明这些基因座在法医学应用中的人类识别具有实用性。与相关人群的 Y-STR 数据集进行了比较分析，并将单倍型提交给 Y-STR 单倍型参考数据库（YHRD）。
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