Rafiq Isma, Parthasarathy Hari, Tremlett Catherine, Freeman Leisa J, Mullin Michael
Department Cardiology, Norfolk & Norwich University NHS Hospital.
Department of Microbiology Norfolk & Norwich University NHS Hospital.
Cardiovasc Revasc Med. 2011 May-Jun;12(3):184-186. doi: 10.1016/j.carrev.2010.03.082. Epub 2010 Oct 20.
First case of infective endocarditis on a percutaneous aortic valve replacement due to Moraxalla nonliquefaciens in 64 year old woman. It was successfully treated medically with antibiotics. She had not suitable for surgical aortic valve replacement due to 3 sternotomies for thymoma resection and subsequent radiotherapy with blocked major thoracic veins. Due to her azathioprine immunosuppresion (myasthenia) she may have been at increased endocarditis risk. We suggest prophylactic antibiotics at implant for this group in future.
64岁女性因不动杆菌属导致经皮主动脉瓣置换术后发生感染性心内膜炎的首例病例。通过抗生素治疗成功治愈。由于曾因胸腺瘤切除术进行过3次胸骨切开术及随后的放疗导致主要胸段静脉阻塞，她不适合进行外科主动脉瓣置换。由于她服用硫唑嘌呤进行免疫抑制（治疗重症肌无力），她可能感染性心内膜炎风险增加。我们建议未来对此类患者在植入时使用预防性抗生素。
