Department of Psychiatry, Division of Geriatric Psychiatry, University of California, La Jolla, San Diego, CA 92093, USA.
Clin Geriatr Med. 2011 May;27(2):171-91. doi: 10.1016/j.cger.2011.01.003. Epub 2011 Mar 25.
Attention has been drawn to the potential risks of several medications in the long-term care setting. Most of these medications deemed as inappropriate affect the central nervous system and are indicated only for select populations with specific conditions. Many of these drugs are prescribed without clear indications and continued indefinitely without critical decision-making about the potentially salutary effects of discontinuing medications. This article describes the increasing awareness of potentially inappropriate prescribing in the long-term care setting and reviews the rationale for why various types of medications are deemed inappropriate, with a focus on agents that affect central nervous system functioning.
人们已经注意到长期护理环境中几种药物的潜在风险。这些被认为不合适的药物大多数影响中枢神经系统，并且仅适用于具有特定条件的特定人群。许多这些药物在没有明确指示的情况下开处方，并在没有关于停止用药可能有益效果的关键决策的情况下无限期地继续使用。本文描述了人们对长期护理环境中潜在不适当处方的认识不断提高，并回顾了为什么各种类型的药物被认为不合适的原因，重点是影响中枢神经系统功能的药物。
