Center for Reproductive Health, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45219, USA.
Fertil Steril. 2011 Jun 30;95(8):2778-80. doi: 10.1016/j.fertnstert.2011.05.024. Epub 2011 Jun 8.
We evaluated the rate of blastocyst development in day 3 embryos with appropriate cellular division and investigated whether maternal age modified the effect of embryo fragmentation on blastulation. Our data showed a significant negative correlation between the degree of embryo fragmentation and rate of blastocyst development, but age did not exert an effect on the degree of fragmentation in embryos with appropriate cleaving status, nor did it modify the significant effect embryo fragmentation had on blastocyst formation.
我们评估了具有适当细胞分裂的第 3 天胚胎的囊胚发育率,并研究了母体年龄是否改变了胚胎碎片对囊胚形成的影响。我们的数据显示,胚胎碎片的程度与囊胚发育率之间存在显著的负相关,但年龄对具有适当分裂状态的胚胎的碎片程度没有影响,也没有改变胚胎碎片对囊胚形成的显著影响。