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将低等级第三天胚胎进行碎片化处理，可导致碎片持续减少，但不能提高胚胎的致密化或囊胚形成率。

Defragmentation of low grade day 3 embryos resulted in sustained reduction in fragmentation, but did not improve compaction or blastulation rates.

机构信息

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, St. Luke's Roosevelt Hospital Center, Columbia University College Of Physicians and Surgeons, New York, New York 10019, USA.

出版信息

Fertil Steril. 2010 Nov;94(6):2406-8. doi: 10.1016/j.fertnstert.2010.03.014. Epub 2010 Apr 18.

DOI:10.1016/j.fertnstert.2010.03.014
PMID:20403590
Abstract

In a prospective randomized fashion, this study evaluated embryo development in vitro after defragmentation versus assisted hatching alone of low grade day 3 embryos. Although a sustained decrease in day 5 fragmentation was observed in the defragmented group versus the assisted hatching only group, no difference in compaction rates or blastula formation rates were appreciated.

摘要

本研究采用前瞻性随机方法，评估了低评分第三天胚胎行碎片化松解与单纯辅助孵化后体外胚胎发育情况。尽管与单纯辅助孵化组相比，碎片化松解组第 5 天碎片持续减少，但胚胎致密化率和囊胚形成率无差异。

相似文献

1
Defragmentation of low grade day 3 embryos resulted in sustained reduction in fragmentation, but did not improve compaction or blastulation rates.将低等级第三天胚胎进行碎片化处理，可导致碎片持续减少，但不能提高胚胎的致密化或囊胚形成率。
Fertil Steril. 2010 Nov;94(6):2406-8. doi: 10.1016/j.fertnstert.2010.03.014. Epub 2010 Apr 18.
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引用本文的文献

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Reprod Biol Endocrinol. 2024 May 14;22(1):55. doi: 10.1186/s12958-024-01217-7.
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Thinning or Opening: A Randomized Sibling-Embryo Pilot Trial on the Efficacy of Two Laser-Assisted Hatching Modes During the Extended Culture of Highly Fragmented Cleavage Embryos.变薄或开口：两种激光辅助孵化模式在延长培养高度碎片化卵裂胚胎中的功效的随机同卵胚胎试验。
Front Endocrinol (Lausanne). 2022 Jun 27;13:927834. doi: 10.3389/fendo.2022.927834. eCollection 2022.
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Laser-assisted hatching in lower grade cleavage stage embryos improves blastocyst formation: results from a retrospective study.
激光辅助孵化在低评分卵裂期胚胎中提高囊胚形成率：一项回顾性研究的结果。
J Ovarian Res. 2021 Jul 15;14(1):94. doi: 10.1186/s13048-021-00844-7.
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