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胸椎肌纤维母细胞瘤:病例报告及文献复习。

Myopericytoma of the thoracic spine: a case report and review of literature.

机构信息

Department of Orthopaedics, Dr. Hedgewar Arogya Sansthan, Karkardooma, New Delhi 110032, India.

出版信息

Spine J. 2013 Nov;13(11):e23-7. doi: 10.1016/j.spinee.2013.06.050. Epub 2013 Sep 14.

DOI:10.1016/j.spinee.2013.06.050
PMID:24045161
Abstract

BACKGROUND CONTEXT

Myopericytoma is a recently proposed term to describe a group of tumors originating from perivascular myoid cells. The tumor is most commonly located in the subcutaneous tissues and dermis of the extremities. Myopericytoma involving the skeletal system is a very rare entity, with only two such cases previously reported in literature.

PURPOSE

To present only the third reported case of myopericytoma of the spine along with a review of literature.

STUDY DESIGN

Case report with and review of literature.

METHODS

We report the case of a 50-year-old woman who presented with pain in the back with gradual onset of paraparesis. Magnetic resonance imaging showed ill-defined signal changes in the body and posterior elements of the vertebrae with epidural soft tissue mass encasing the spinal cord.

RESULTS

The patient underwent excision of the lesion with spinal fusion followed by a short course of radiotherapy. The patient recovered functional power after surgery, and at 32-month follow-up, there is no radiological evidence of recurrence of the lesion.

CONCLUSIONS

Myopericytoma should be considered in the differential diagnosis of lytic lesions of the spine. Surgery is curative; however, a short course of chemotherapy or radiotherapy may be required to prevent recurrent disease in case of incomplete tumor excision.

摘要

背景

肌纤维母细胞瘤是最近提出的一个术语,用于描述一组起源于血管周肌样细胞的肿瘤。该肿瘤最常见于四肢的皮下组织和真皮。涉及骨骼系统的肌纤维母细胞瘤是一种非常罕见的实体瘤,文献中仅报道过两例。

目的

仅报道第三例脊柱肌纤维母细胞瘤病例,并进行文献复习。

研究设计

病例报告并文献复习。

方法

我们报告了一例 50 岁女性患者,以逐渐出现的截瘫为首发症状的背痛。磁共振成像显示椎体体部和后缘有不明确的信号改变,硬膜外软组织肿块包裹脊髓。

结果

患者接受了病变切除术和脊柱融合术,随后进行了短期放疗。患者术后恢复了功能,32 个月随访时,无病变复发的影像学证据。

结论

在脊柱溶骨性病变的鉴别诊断中应考虑肌纤维母细胞瘤。手术是治愈性的;然而,如果肿瘤切除不完全,可能需要短期化疗或放疗来预防复发性疾病。

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