Schoonover Robert W, Anastasio Mark A
Medical Imaging Research Center, Illinois Institute of Technology, Chicago, Illinois, USA.
J Opt Soc Am A Opt Image Sci Vis. 2011 Jun 1;28(6):1114-20. doi: 10.1364/JOSAA.28.001114.
Photoacoustic tomography (PAT), also known as thermoacoustic or optoacoustic tomography, is a rapidly emerging biomedical imaging technique that combines optical image contrast with ultrasound detection principles. Most existing reconstruction algorithms for PAT assume the object of interest possesses homogeneous acoustic properties. The images produced by such algorithms can contain significant distortions and artifacts when the object's acoustic properties are spatially variant. In this work, we establish an image reconstruction formula for PAT applications in which a planar detection surface is employed and the to-be-imaged optical absorber is embedded in a known planar layered acoustic medium. The reconstruction formula is exact in a mathematical sense and accounts for multiple acoustic reflections between the layers of the medium. Computer-simulation studies are conducted to demonstrate and investigate the proposed method.
光声断层扫描（PAT），也被称为热声或光声断层扫描，是一种迅速兴起的生物医学成像技术，它将光学图像对比度与超声检测原理相结合。大多数现有的PAT重建算法假定感兴趣的物体具有均匀的声学特性。当物体的声学特性在空间上变化时，此类算法生成的图像可能会包含显著的失真和伪影。在这项工作中，我们建立了一个用于PAT应用的图像重建公式，其中采用平面检测表面，且待成像的光吸收体嵌入已知的平面分层声学介质中。该重建公式在数学意义上是精确的，并考虑了介质各层之间的多次声反射。进行了计算机模拟研究以演示和研究所提出的方法。
