Department of Orthopaedic and Trauma Surgery, University Hospital Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany.
Int Orthop. 2012 Jan;36(1):111-7. doi: 10.1007/s00264-011-1288-5. Epub 2011 Jun 4.
Corpectomy and implantation of titanium cages is standard in pathological fracture treatment but additional single ventral instrumentation remains controversial with regard to rotational stability.
This study included 45 patients suffering from vertebral metastases with spinal stenosis, instability and/or neurological deficits secondary to pathological lumbar spine fractures and bone mineral density (BMD) ≥ 1.20 g/cm(2). The clinical results of a single stage anterior decompression with corpectomy defect restoration with titanium cage and single double rod system in patients were evaluated at mean 36 months postoperatively with follow-up neurological and radiological exams at three months then every six months. Evaluation of neurological recovery included grading following a modified Frankel scale. Contentment, disability and actual pain were evaluated using the visual analogue scale (VAS) and Oswestry disability index (ODI). BMD was measured using dual-energy X-ray absorptiometry (DXA).
Postoperative neurological evaluations showed improvement in all patients. In the radiological follow-up in 40 patients (89%) findings were similar compared to the postoperative control. In five patients (11%) a loss of correction at a mean of 8° degrees (Cobb angle) secondary to cage subsidence occurred. No breakage of the device or displacement of the instrumentation was seen. Overall the Frankel scale improved 0.65 points (p < 0.05) and the ODI improved 40.69 points (p < 0.05).
In lumbar spine fractures of metastatic origin with stenosis, instability and/or neurological deficit, a single stage ventral decompression and instrumentation in patients with BMD ≥ 1.20 g/cm(2) should be considered.
椎体切除术和钛笼植入是病理性骨折治疗的标准方法,但对于旋转稳定性,额外的单一前路内固定仍存在争议。
本研究纳入了 45 例因病理性腰椎骨折导致脊柱狭窄、不稳定和/或神经功能缺损的脊柱转移瘤患者,其骨密度(BMD)≥1.20g/cm²。在平均 36 个月的术后随访中,对患者进行了单阶段前路减压、钛笼和单双棒系统治疗的临床疗效评估,随访时进行了神经和影像学检查,随后每 6 个月进行一次。神经恢复的评估包括采用改良的 Frankel 量表进行分级。采用视觉模拟评分(VAS)和 Oswestry 残疾指数(ODI)评估满意度、残疾和实际疼痛。采用双能 X 线吸收法(DXA)测量 BMD。
术后神经学评估显示所有患者均有改善。在 40 例患者(89%)的影像学随访中,与术后即刻相比,发现相似。5 例患者(11%)发生了平均 8°(Cobb 角)的矫正丢失,这是由于笼沉降引起的。未发现器械断裂或移位。总体而言,Frankel 量表提高了 0.65 分(p<0.05),ODI 提高了 40.69 分(p<0.05)。
对于 BMD≥1.20g/cm²的合并狭窄、不稳定和/或神经功能缺损的转移性起源的腰椎骨折患者,应考虑采用单阶段前路减压和内固定。