Guo Yongyong, Wu Kusheng, Huo Xia, Xu Xijin
Department of Cell Biology, Shantou University Medical College, Guandong, P.R. China.
J Environ Health. 2011 May;73(9):22-5.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants released from the incomplete combustion of fossil fuels and are always found as a mixture of individual compounds. Due to economic growth and a sharp increase in energy consumption in recent years, large quantities of PAHs have been released into the environment worldwide. Because many PAHs and their derivatives are strongly potent carcinogens, or mutagens, PAHs have been extensively studied recently. The authors reviewed the origin and distribution of PAHs in atmosphere, soil, and sediment in natural environments. PAHs represent a class of toxicological compounds that can create a variety of hazardous effects in vivo/in vitro, including genotoxicity, immunotoxicity, developmental toxicity, and carcinogenesis, which the authors also describe.
多环芳烃（PAHs）是化石燃料不完全燃烧释放出的普遍存在的污染物，且总是以单个化合物的混合物形式存在。由于近年来经济增长和能源消耗急剧增加，大量多环芳烃已被释放到全球环境中。因为许多多环芳烃及其衍生物是强效致癌物或诱变剂，所以近年来对多环芳烃进行了广泛研究。作者综述了自然环境中大气、土壤和沉积物中多环芳烃的来源和分布。多环芳烃是一类毒理学化合物，可在体内/体外产生多种有害影响，包括遗传毒性、免疫毒性、发育毒性和致癌作用，作者也对此进行了描述。
