Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Box 3837, Durham, NC 27710, USA.
Expert Opin Pharmacother. 2011 Jul;12(10):1623-32. doi: 10.1517/14656566.2011.585459. Epub 2011 Jun 6.
Depression is a heterogeneous illness affecting large numbers of patients with far reaching effects on both psychiatric and medical outcomes as well as quality of life. Knowledge about the different treatment modalities used to treat depression is important to all physicians.
This article expands on one such treatment option, mirtazapine. The paper examines this medication's medicinal chemistry, pharmacological properties as well as the efficacy of the medication compared to other commonly used antidepressants.
Mirtazapine is a medication unlike other agents used for depression both in its mechanism of action as well as its side effects. Knowing these distinct characteristics will enable physicians to better utilize this agent for the benefit of their patients.
抑郁症是一种影响大量患者的异质性疾病,对精神和医疗结果以及生活质量都有深远的影响。了解治疗抑郁症的不同方法对所有医生都很重要。
本文扩展了一种这样的治疗选择,即米氮平。本文研究了这种药物的药物化学、药理学特性以及与其他常用抗抑郁药相比的疗效。
米氮平是一种与其他用于治疗抑郁症的药物不同的药物,无论是在作用机制还是副作用方面。了解这些独特的特征将使医生能够更好地利用这种药物为患者带来好处。