Holst Lars Broksø, Perner Anders
Anæstesiologisk Afdeling, Hvidovre Hospital, Denmark.
Ugeskr Laeger. 2011 Jun 6;173(23):1632-4.
Critically ill non-bleeding patients often receive red blood cell transfusions in the intensive care unit because of anaemia. The evidence that transfusion leads to improved outcome is limited and the treatment may be harmful to some of these patients. Current recommendations support a restrictive transfusion strategy. Additional randomised clinical trials are needed to elucidate the association between specific haemoglobin levels, transfusion and morbidity and mortality in critically ill patients including those with severe sepsis and acute coronary syndrome.
危重症非出血患者常因贫血在重症监护病房接受红细胞输注。输血能改善预后的证据有限,且该治疗可能对部分此类患者有害。目前的建议支持限制性输血策略。需要更多随机临床试验来阐明特定血红蛋白水平、输血与危重症患者(包括严重脓毒症和急性冠状动脉综合征患者)发病率及死亡率之间的关联。