Department of Biology, University of Maryland, College Park, MD 20742, USA.
Curr Opin Neurobiol. 2011 Oct;21(5):745-51. doi: 10.1016/j.conb.2011.05.008. Epub 2011 Jun 7.
Many animals use the interaural time differences (ITDs) to locate the source of low frequency sounds. The place coding theory proposed by Jeffress has long been a dominant model to account for the neural mechanisms of ITD detection. Recent research, however, suggests a wider range of strategies for ITD coding in the binaural auditory brainstem. We discuss how ITD is coded in avian, mammalian, and reptilian nervous systems, and review underlying synaptic and cellular properties that enable precise temporal computation. The latest advances in recording and analysis techniques provide powerful tools for both overcoming and utilizing the large field potentials in these nuclei.
许多动物利用两耳时间差（ITD）来定位低频声音的声源。Jeffress 提出的位置编码理论长期以来一直是解释 ITD 检测神经机制的主导模型。然而，最近的研究表明，在双侧听觉脑干中存在更广泛的 ITD 编码策略。我们讨论了 ITD 在鸟类、哺乳动物和爬行动物神经系统中的编码方式，并回顾了使精确时间计算成为可能的突触和细胞特性。最新的记录和分析技术的进步为克服和利用这些核团中的大场电位提供了强大的工具。
