Miura M, Kitamura T
Brain Res. 1979 Feb 23;162(2):261-72. doi: 10.1016/0006-8993(79)90288-9.
Projections of the carotid sinus nerve (CSN) onto medullary neurones were studied with intracellular recording. Three types of postsynaptic potentials (EPSP, EP-IPSP and IPSP) were recorded by stimulation of the ipsilateral CSN. Of the total of 121 neurones, positions of 54 were identified by intracellular dye. The other 67 were positioned by extrapolation. They were distributed over 5 medullary nuclei: (1) nucleus of the solitary tract (NTS); (2) paramedian reticular nucleus (NPR); (3) perihypoglossal nucleus (PXII); (4) lateral tegmental field (FTL); and (5) nucleus ambiguus. Since penetration of microelectrodes and injection of dye into the NTS neurones was difficult, neurones of the other 4 nuclei were examined. The IPSPs were dominant in small NPR neurones, while the EPSPs were dominant in large neurones of the other 3 nuclei. Both the NA and PXII neurones showed forms of a motor type neurone, while the FTL neurones showed various forms. The EPSPs with onset latency as short as 2-4 msec were frequently recorded in different nuclei. This strongly suggests that the CSN projects monosynaptically onto different nuclei in the medulla.
采用细胞内记录法研究了颈动脉窦神经（CSN）向延髓神经元的投射。通过刺激同侧CSN记录到三种类型的突触后电位（兴奋性突触后电位、兴奋性-抑制性突触后电位和抑制性突触后电位）。在总共121个神经元中，54个神经元的位置通过细胞内染料标记确定。另外67个通过推断定位。它们分布在5个延髓核中：（1）孤束核（NTS）；（2）旁正中网状核（NPR）；（3）舌下神经周核（PXII）；（4）外侧被盖区（FTL）；（5）疑核。由于微电极插入和向NTS神经元注射染料困难，因此对其他4个核的神经元进行了检查。抑制性突触后电位在小的NPR神经元中占主导，而兴奋性突触后电位在其他3个核的大神经元中占主导。疑核和舌下神经周核的神经元均表现为运动型神经元的形式，而外侧被盖区的神经元表现出多种形式。在不同核中经常记录到起始潜伏期短至2 - 4毫秒的兴奋性突触后电位。这强烈表明CSN向延髓的不同核发出单突触投射。
