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帕金森病:症状、治疗与研究

Parkinson's: symptoms, treatments and research.

作者信息

Heisters Daiga

机构信息

Parkinson's UK, London, UK.

出版信息

Br J Nurs. 2011;20(9):548-54. doi: 10.12968/bjon.2011.20.9.548.

Abstract

Parkinson's is a incurable progressive neurological condition caused by a degeneration of dopamine-producing cells. The most common symptoms of the condition include slowness of movement, tremor and muscle stiffness; other symptoms include sleep difficulties, depression and anxiety. Parkinson's is usually controlled by medication but other treatments and therapies, such as occupational therapy, physiotherapy and speech and language therapy, can also be effective in controlling and managing symptoms. The timing of this medication is key to the successful management of Parkinson's. Delays to initiating medication or missed doses can have serious consequences, and it can take some time for symptoms to stabilize. Research into treatments for Parkinson's and, ultimately, finding a cure for the condition, is ongoing. Parkinson's UK researchers are working on projects to identify the causes of cell death and tests to detect the condition at its earliest possible stage. Current treatments can help to ease the symptoms but none can repair the damage in the brain or slow the progress of the condition; now, Parkinson's UK researchers are working to develop new treatments that can.

摘要

帕金森病是一种无法治愈的进行性神经疾病,由产生多巴胺的细胞退化引起。该疾病最常见的症状包括运动迟缓、震颤和肌肉僵硬;其他症状包括睡眠困难、抑郁和焦虑。帕金森病通常通过药物控制,但其他治疗方法,如职业治疗、物理治疗和言语及语言治疗,在控制和管理症状方面也可能有效。药物服用的时间是成功管理帕金森病的关键。延迟开始用药或漏服剂量可能会产生严重后果,而且症状稳定可能需要一些时间。对帕金森病治疗方法的研究以及最终找到治愈该疾病的方法正在进行中。英国帕金森病研究人员正在开展项目,以确定细胞死亡的原因,并进行测试以便在尽可能早的阶段检测出该疾病。目前的治疗方法有助于缓解症状,但没有一种能修复大脑中的损伤或减缓病情发展;现在,英国帕金森病研究人员正在努力开发能够做到这一点的新治疗方法。

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