儿童急性白血病或实体瘤化疗期间细菌和真菌感染的管理指南：2010年有哪些可用的？
Guidelines for the management of bacterial and fungal infections during chemotherapy for pediatric acute leukemia or solid tumors: what is available in 2010?
作者信息
Castagnola Elio, Caviglia Ilaria, Haupt Riccardo
机构信息
Infectious Diseases Unit, Oncohematology Department, G. Gaslini Children's Hospital, Genoa;
出版信息
Pediatr Rep. 2011 Feb 24;3(1):e7. doi: 10.4081/pr.2011.e7.
Abstract
Febrile episodes and infections represent important complications during antineoplastic chemotherapy for pediatric neoplastic diseases. In the last years many international association published guidelines for the management of these complications in adults, but no document of this type was prepared for children. One of the major causes of this situation is probably the very low number of pediatric clinical trials with adequate power and design. The paper summarizes guidelines provided for the management of infectious complications in adults with cancer by different international and will comment on how much they may be translated in the management of pediatric patients.
摘要
发热发作和感染是儿童肿瘤疾病抗肿瘤化疗期间的重要并发症。在过去几年里，许多国际协会发布了成人这些并发症管理的指南，但尚未为儿童编写此类文件。造成这种情况的主要原因之一可能是具有足够效力和设计的儿科临床试验数量非常少。本文总结了不同国际组织为癌症成人患者感染并发症管理提供的指南，并将评论它们在儿科患者管理中可转化的程度。
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