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手性单（N-杂环卡宾）钯和金配合物的合成具有 1,1'-联苯骨架及其在催化中的应用。

Synthesis of chiral mono(N-heterocyclic carbene) palladium and gold complexes with a 1,1'-biphenyl scaffold and their applications in catalysis.

机构信息

Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 MeiLong Road, Shanghai 200237, People's Republic of China.

出版信息

Beilstein J Org Chem. 2011;7:555-64. doi: 10.3762/bjoc.7.64. Epub 2011 May 4.

DOI:10.3762/bjoc.7.64
PMID:21647321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3107448/
Abstract

Axially chiral mono(NHC)-Pd(II) and mono(NHC)-Au(I) complexes with one side shaped 1,1'-biphenyl backbone have been prepared from chiral 6,6'-dimethoxybiphenyl-2,2'-diamine. The complexes were characterized by X-ray crystal structure diffraction. The Pd(II) complex showed good catalytic activities in the Suzuki-Miyaura and Heck-Mizoroki coupling reactions, and the (S)-Au(I) complexes also showed good catalytic activities in the asymmetric intramolecular hydroamination reaction to give the corresponding product in moderate ee.

摘要

轴手性单(NHC)-Pd(II)和单(NHC)-Au(I)配合物，具有一个由 1,1'-联苯骨架塑造的一侧，已从手性 6,6'-二甲氧基联苯-2,2'-二胺制备得到。这些配合物通过 X 射线晶体结构衍射进行了表征。Pd(II)配合物在 Suzuki-Miyaura 和 Heck-Mizoroki 偶联反应中表现出良好的催化活性，(S)-Au(I)配合物在不对称分子内氨化反应中也表现出良好的催化活性，以中等对映选择性得到相应产物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/72493902b178/Beilstein_J_Org_Chem-07-555-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/7e96dd7b2d13/Beilstein_J_Org_Chem-07-555-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/0393f3fda62a/Beilstein_J_Org_Chem-07-555-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/d8b6a55192e0/Beilstein_J_Org_Chem-07-555-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/a1632c3ed6da/Beilstein_J_Org_Chem-07-555-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/99bbcaf2f432/Beilstein_J_Org_Chem-07-555-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/3aa5321aad73/Beilstein_J_Org_Chem-07-555-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/d15a82fb4ddd/Beilstein_J_Org_Chem-07-555-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/8870342855d8/Beilstein_J_Org_Chem-07-555-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/f59ea3808df7/Beilstein_J_Org_Chem-07-555-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/72493902b178/Beilstein_J_Org_Chem-07-555-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/7e96dd7b2d13/Beilstein_J_Org_Chem-07-555-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/0393f3fda62a/Beilstein_J_Org_Chem-07-555-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/d8b6a55192e0/Beilstein_J_Org_Chem-07-555-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/a1632c3ed6da/Beilstein_J_Org_Chem-07-555-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/99bbcaf2f432/Beilstein_J_Org_Chem-07-555-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/3aa5321aad73/Beilstein_J_Org_Chem-07-555-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/d15a82fb4ddd/Beilstein_J_Org_Chem-07-555-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/8870342855d8/Beilstein_J_Org_Chem-07-555-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/f59ea3808df7/Beilstein_J_Org_Chem-07-555-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e142/3107448/72493902b178/Beilstein_J_Org_Chem-07-555-g011.jpg

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