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银杏叶提取物对血管功能和血压的急性影响。

Acute effects of Ginkgo biloba extract on vascular function and blood pressure.

机构信息

Diabetes & Nutritional Sciences Division, School of Medicine, King's College London, London, UK.

出版信息

Plant Foods Hum Nutr. 2011 Sep;66(3):209-11. doi: 10.1007/s11130-011-0234-4.

DOI:10.1007/s11130-011-0234-4
PMID:21647656
Abstract

We investigated whether a single dose of standardized Ginkgo biloba extract (GBE) can improve vascular function. A randomised controlled crossover trial was conducted on 14 young healthy men, who received GBE or placebo. The digital volume pulse was monitored to measure reflection index (DVP-RI) and stiffness index (DVP-SI) and peripheral augmentation index (pAIx) was assessed using radial pulse wave analysis at baseline and 2, 4 and 6 h after treatment. DVP-SI was slightly higher 2 h following GBE compared to placebo (P < 0.05); other outcome variables were unaffected by treatment.

摘要

我们研究了单次剂量标准化银杏叶提取物(GBE)是否可以改善血管功能。在 14 名年轻健康男性中进行了一项随机对照交叉试验,他们分别接受 GBE 或安慰剂治疗。通过监测数字体积脉搏来测量反射指数(DVP-RI)和硬度指数(DVP-SI),并使用桡动脉脉搏波分析在治疗后 2、4 和 6 小时评估外周增强指数(pAIx)。与安慰剂相比,GBE 治疗后 2 小时 DVP-SI 略有升高(P<0.05);其他结果变量不受治疗影响。

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