Comprehensive Stroke Program, Department of Neurology, Wayne State University School of Medicine, 8C-UHC, 4201 St. Antoine, Detroit, MI 48201, USA.
Neurotherapeutics. 2011 Jul;8(3):503-14. doi: 10.1007/s13311-011-0052-2.
Extracranial carotidartery stenosis is an important cause of stroke that often needs treatment with carotid revascularization. To prevent stroke recurrence, carotid endarterectomy has been well-established for many years in treating symptomatic high- and moderate-grade stenosis. Carotid stenting is an appealing, less invasive alternative to carotid endarterectomy, and several recent trials have compared the efficacy of the 2 procedures in patients with carotid stenosis. Carotid artery stenting has emerged as an important mode of therapy for high-risk patients with symtomatic high-grade stenosis. This review focuses on the current data available that will enable the clinician to decide optimal treatment strategies for patients with carotid stenosis.
颅外颈动脉狭窄是中风的一个重要原因,常需要通过颈动脉血运重建来治疗。为了预防中风复发,颈动脉内膜切除术多年来一直被用于治疗有症状的高、中度狭窄。颈动脉支架置入术是一种有吸引力的、创伤较小的颈动脉内膜切除术替代方法,几项最近的试验比较了这两种方法在颈动脉狭窄患者中的疗效。颈动脉支架置入术已成为治疗有症状的高危重度狭窄患者的一种重要治疗方式。本文综述了目前可用的研究数据,以帮助临床医生为颈动脉狭窄患者制定最佳的治疗策略。