Meschia James F, Klaas James P, Brown Robert D, Brott Thomas G
Department of Neurology, Mayo Clinic, Jacksonville, FL.
Department of Neurology, Mayo Clinic, Rochester, MN.
Mayo Clin Proc. 2017 Jul;92(7):1144-1157. doi: 10.1016/j.mayocp.2017.02.020.
Medical therapies for the prevention of stroke have advanced considerably in the past several years. There can also be a role for mechanical restoration of the lumen by endarterectomy or stenting in selected patients with high-grade atherosclerotic stenosis of the extracranial carotid artery. Endarterectomy is generally recommended for patients with high-grade symptomatic carotid stenosis. Stenting is considered an option for patients at high risk of complications with endarterectomy. Whether revascularization is better than contemporary medical therapy for asymptomatic extracranial carotid stenosis is a subject of several ongoing randomized clinical trials in the United States and internationally.
在过去几年中,预防中风的医学疗法有了显著进展。对于某些患有颅外颈动脉高度动脉粥样硬化狭窄的患者,通过动脉内膜切除术或支架置入术进行管腔的机械性恢复也能发挥作用。动脉内膜切除术通常推荐用于有症状的高度颈动脉狭窄患者。对于动脉内膜切除术有高并发症风险的患者,支架置入术被视为一种选择。对于无症状的颅外颈动脉狭窄,血管重建术是否优于当代医学疗法是美国和国际上正在进行的几项随机临床试验的主题。