Suppr超能文献

[喉软骨肉瘤。1999年以来在弗赖堡积累的经验]

[Chondrosarcoma of the larynx. Experience gained in Freiburg since 1999].

作者信息

Boedeker C C, Maier W, Boedeker M, Ridder G J, Klenzner T, Kayser G, Offergeld C

机构信息

Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde und Poliklinik, Universitätsklinikum Freiburg.

出版信息

HNO. 2011 Apr;59(4):352-9. doi: 10.1007/s00106-010-2243-2.

Abstract

BACKGROUND

Chondrosarcomas are rare tumors of the head and neck. Nevertheless, they display the most common non-epithelial malignancy of the larynx.

MATERIALS AND METHODS

Between 1999 and February 2010 we treated six patients with laryngeal chondrosarcoma. The group included two female and four male patients ranging in age from 54 to 82 years.

RESULTS

An 82-year-old female patient died 3 months after diagnosis and tracheostomy due to other underlying diseases. An 82-year-old male patient underwent primary radiation therapy. In the other patients, we performed a modified hemilaryngektomy in three cases and a laryngectomy in one. In those four cases, there were no signs of recurrent disease 50, 85, 87 and 95 months after surgery, respectively. There were no local or distant metastases.

CONCLUSIONS

Chondrosarcomas of the larynx are slow growing neoplasms. Metastases occur in less than 3% of cases. Complete resection is the therapy of choice. Function-preserving surgical approaches should be favoured.

摘要

背景

软骨肉瘤是头颈部罕见的肿瘤。然而,它们却是喉最常见的非上皮性恶性肿瘤。

材料与方法

1999年至2010年2月期间,我们治疗了6例喉软骨肉瘤患者。该组包括2名女性和4名男性患者,年龄在54岁至82岁之间。

结果

一名82岁女性患者在诊断及气管切开术后3个月因其他基础疾病死亡。一名82岁男性患者接受了原发性放射治疗。在其他患者中,3例行改良半喉切除术,1例行全喉切除术。在这4例患者中,术后分别在50、85、87和95个月时均无疾病复发迹象。无局部或远处转移。

结论

喉软骨肉瘤是生长缓慢的肿瘤。转移发生率低于3%。完整切除是首选治疗方法。应优先选择保留功能的手术方式。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验