Boedeker C C, Maier W, Boedeker M, Ridder G J, Klenzner T, Kayser G, Offergeld C
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde und Poliklinik, Universitätsklinikum Freiburg.
HNO. 2011 Apr;59(4):352-9. doi: 10.1007/s00106-010-2243-2.
Chondrosarcomas are rare tumors of the head and neck. Nevertheless, they display the most common non-epithelial malignancy of the larynx.
Between 1999 and February 2010 we treated six patients with laryngeal chondrosarcoma. The group included two female and four male patients ranging in age from 54 to 82 years.
An 82-year-old female patient died 3 months after diagnosis and tracheostomy due to other underlying diseases. An 82-year-old male patient underwent primary radiation therapy. In the other patients, we performed a modified hemilaryngektomy in three cases and a laryngectomy in one. In those four cases, there were no signs of recurrent disease 50, 85, 87 and 95 months after surgery, respectively. There were no local or distant metastases.
Chondrosarcomas of the larynx are slow growing neoplasms. Metastases occur in less than 3% of cases. Complete resection is the therapy of choice. Function-preserving surgical approaches should be favoured.
软骨肉瘤是头颈部罕见的肿瘤。然而,它们却是喉最常见的非上皮性恶性肿瘤。
1999年至2010年2月期间,我们治疗了6例喉软骨肉瘤患者。该组包括2名女性和4名男性患者,年龄在54岁至82岁之间。
一名82岁女性患者在诊断及气管切开术后3个月因其他基础疾病死亡。一名82岁男性患者接受了原发性放射治疗。在其他患者中,3例行改良半喉切除术,1例行全喉切除术。在这4例患者中,术后分别在50、85、87和95个月时均无疾病复发迹象。无局部或远处转移。
喉软骨肉瘤是生长缓慢的肿瘤。转移发生率低于3%。完整切除是首选治疗方法。应优先选择保留功能的手术方式。