Bernal Sprekelsen M, Störkel S
Clínica Universitaria de ORL, Facultad de Medicina de Mainz.
Acta Otorrinolaringol Esp. 1990 Jul-Aug;41(4):253-6.
Two malignant tumors of cartilaginous origin are presented. Both demonstrated all histologic criteria of chondrosarcomas. Chondrosarcoma of the larynx seem to arise from hyaline cartilage, being the cricoid the mostly involved cartilage. The growth rate is very low, so that the first symptoms, as hoarseness or dyspnea, may be anodyne. The survival rates are directly related to histological grading. Chondrosarcoma are usually of low-grade malignancy. Local growth is predominant, metastarization has been described for high-grade types. Local recurrence may occur even after years. Surgery is the treatment of choice.
本文报告了两例软骨源性恶性肿瘤。两者均符合软骨肉瘤的所有组织学标准。喉软骨肉瘤似乎起源于透明软骨,环状软骨是最常受累的软骨。其生长速度非常缓慢,因此最初的症状,如声音嘶哑或呼吸困难,可能并不明显。生存率与组织学分级直接相关。软骨肉瘤通常为低级别恶性肿瘤。以局部生长为主,高级别类型有转移的报道。即使数年之后也可能发生局部复发。手术是首选的治疗方法。