从细菌性阴道病病例中分离出的阴道加德纳菌的生物型和毒力因子。
Biotypes and virulence factors of Gardnerella vaginalis isolated from cases of bacterial vaginosis.
作者信息
Udayalaxmi J, Bhat G K, Kotigadde S
机构信息
Department of Microbiology, Kasturba Medical College, Manipal University, Mangalore 575 001, India.
出版信息
Indian J Med Microbiol. 2011 Apr-Jun;29(2):165-8. doi: 10.4103/0255-0857.81798.
The present study was conducted to correlate the biotypes of Gardnerella vaginalis strains isolated from cases of bacterial vaginosis and their virulence factors. Thirty-two strains of G. vaginalis isolated from cases of bacterial vaginosis were biotyped. Adherence to vaginal epithelial cells, biofilm production, surface hydrophobicity, phospholipase C and protease activity were tested on these isolates. Biotype 1 was the most prevalent (8; 25%), followed by biotype 2 (7; 21.9%) and biotypes 5 and 8 (5; 15.6%). We did not find any statistical correlation between G. vaginalis biotypes and its virulence factors. Virulence factors expressed by G. vaginalis were not associated with a single biotype.
本研究旨在关联从细菌性阴道病病例中分离出的阴道加德纳菌菌株的生物型及其毒力因子。对从细菌性阴道病病例中分离出的32株阴道加德纳菌进行了生物分型。对这些分离株进行了阴道上皮细胞黏附、生物膜形成、表面疏水性、磷脂酶C和蛋白酶活性的检测。生物型1最为常见（8株；25%），其次是生物型2（7株；21.9%）以及生物型5和8（各5株；15.6%）。我们未发现阴道加德纳菌生物型与其毒力因子之间存在任何统计学关联。阴道加德纳菌表达的毒力因子与单一生物型无关。
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