French Institute for Public Health Surveillance, St Maurice, France.
J Occup Environ Med. 2011 Jun;53(6 Suppl):S103-7. doi: 10.1097/JOM.0b013e31821b1d68.
Concern has been raised about the potential impact of nanomaterials exposure on human health, and France has decided to implement a timely epidemiological surveillance tool of workers likely to be exposed to engineered nanomaterials that could accompany the development of nanotechnologies.
A comprehensive review of the toxicological and epidemiological literature has been conducted together with an exploratory study among French companies producing or handling nanoobjects.
A double surveillance system is proposed consisting of a prospective cohort survey and repeated cross-sectional studies. The aim of the cohort is (1) to monitor long-term health effects and (2) to allow of further research. Setting-up an exposure registry is the first planned step.
The protocol is about to be submitted to the French Government for approval and funding.
人们对纳米材料暴露对人类健康可能产生的影响表示担忧，法国已决定采用一种及时的流行病学监测工具，对可能接触到工程纳米材料的工人进行监测，以伴随纳米技术的发展。
对毒理学和流行病学文献进行了全面审查，并对法国生产或处理纳米物体的公司进行了探索性研究。
提出了一个双重监测系统，包括前瞻性队列研究和重复横断面研究。该队列的目的是：（1）监测长期健康影响；（2）为进一步的研究提供帮助。建立暴露登记册是计划的第一步。
该方案即将提交法国政府批准和资助。
