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采用超根治性手术治疗的原发性子宫颈恶性黑色素瘤:一例报告

Primary malignant melanoma of the uterine cervix treated with ultraradical surgery: a case report.

作者信息

Calderón-Salazar Luz, Cantú de Leon David, Perez Montiel Delia, Almogabar-Villagrán Erika, Villavicencio Verónica, Cetina Lucely

机构信息

Department of Gynecologic Oncology, Instituto Nacional de Cancerologia, 14080 Mèxico, Mexico.

出版信息

ISRN Obstet Gynecol. 2011;2011:683020. doi: 10.5402/2011/683020. Epub 2010 Oct 5.

Abstract

Primary melanomas of the uterine cervix are rare tumors with no more than 60 cases reported in the world literature. Poor prognosis is considered for the neoplasia itself as well as for diagnostic tardiness. There is no standard treatment; however, radical surgery is the treatment cornerstone. Our aim was to present the case of a 34-year-old woman with a primary malignant melanoma in the uterine cervix with affectation of the posterior face of the vagina without metastasis. Total infraelevator pelvic exenteration and adjuvant radiotherapy was performed. The patient was under surveillance for 8 years of followup without evidence of local or distant disease. The majority of case reports found suggests radical hysterectomy as the treatment indicated for these patients. Notwithstanding this, survival is very short when patients are treated in this manner. Based on our results and on those reported in the literature, we propose initial treatment with total pelvic exenteration as optimal management for this neoplasia in its initial form.

摘要

子宫颈原发性黑色素瘤是罕见肿瘤,世界文献报道不超过60例。该肿瘤本身以及诊断延迟均提示预后不良。目前尚无标准治疗方法;然而,根治性手术是治疗的基石。我们的目的是介绍一名34岁女性病例,该患者患有子宫颈原发性恶性黑色素瘤,累及阴道后壁但无转移。实施了全盆腔脏器切除术及辅助放疗。患者接受了8年随访监测,未发现局部或远处疾病迹象。大多数已发表的病例报告表明,根治性子宫切除术是这些患者的治疗方案。尽管如此,采用这种方式治疗的患者生存期很短。基于我们的结果以及文献报道,我们建议对于这种初发形式的肿瘤,初始治疗采用全盆腔脏器切除术作为最佳治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f0b/3101984/0075fa58497c/OBGYN2011-683020.001.jpg

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