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奇美拉分枝杆菌引起一位神经性厌食男性患者类似肺结核的感染。

Mycobacterium chimaera causes tuberculosis-like infection in a male patient with anorexia nervosa.

机构信息

Department of Internal Medicine 2, Klinikum Bayreuth, Bayreuth, Germany.

出版信息

Int J Eat Disord. 2012 Apr;45(3):450-2. doi: 10.1002/eat.20942. Epub 2011 Jun 7.

DOI:10.1002/eat.20942
PMID:21656541
Abstract

Here we present a 27-year-old male patient--with a known prolonged history of anorexia nervosa (AN)--suffering from tuberculosis like infection. At the time he was admitted to clinical treatment, he had developed fever up to 40°C and survived on a body mass index of 11.8. In this case, Mycobacterium chimaera, generally recognized for low pathogenicity, was identified as the causative agent. Remission from lung infection was achieved after antibiotic treatment according to laboratory susceptibility testing while earlier antituberculosis therapies had failed. Because of a large cavity in the upper left lung, surgical excision was necessary to prevent recurrence of lung infection. Moreover, stabilization of the patient general health problem needs to be supported by a lasting psychotherapy.

摘要

在这里,我们呈现一位 27 岁的男性患者,他患有已知的长期厌食症(AN)病史,同时还患有类似结核病的感染。当他入院接受临床治疗时,他已经发烧到 40°C,体重指数仅为 11.8。在这种情况下,我们发现了一种通常被认为致病性较低的耻垢分枝杆菌,它被鉴定为致病原因。根据实验室药敏试验进行抗生素治疗后,肺部感染得到缓解,而之前的抗结核治疗失败了。由于左上肺有一个大空洞,为了防止肺部感染复发,需要进行手术切除。此外,还需要通过持久的心理治疗来支持患者整体健康状况的稳定。

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