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[天然沸石所致尘肺的形态学]

[Morphology of pneumoconiosis induced by natural zeolite].

作者信息

Kruglikov G G, Velichkovskiĭ B T, Garmash T I

出版信息

Gig Tr Prof Zabol. 1990(5):14-7.

PMID:2165972
Abstract

Pneumoconiosis was induced in white rats through intratracheal administration of natural zeolite. It was characterized by intensive phagocytosis of the specks of dust, moderate cytotoxic action on the macrophages, as well as inflammatory processes in the vascular system and alveolar epithelium. Zeolite induced fibrosis did not develop to the extent as in case with quartz induced massive collagen formation.

摘要

通过气管内注入天然沸石在白鼠体内诱发尘肺。其特征为对尘粒的强烈吞噬作用、对巨噬细胞的中度细胞毒性作用以及血管系统和肺泡上皮的炎症过程。沸石诱发的纤维化程度不及石英诱发大量胶原形成时的程度。

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