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[与计算机断层扫描相比,放射免疫闪烁显像在原发性卵巢癌诊断及随访中的价值]

[Value of radioimmunoscintigraphy compared to computed tomography in the diagnosis and follow-up of primary ovarian carcinoma].

作者信息

Barzen G, Cordes M, Langer M, Friedman W, Mayr A C, Felix R

机构信息

Strahlenklinik mit Poliklinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.

出版信息

Rofo. 1990 Jul;153(1):85-91. doi: 10.1055/s-2008-1033338.

DOI:10.1055/s-2008-1033338
PMID:2166319
Abstract

In this prospective study the diagnostic merit of radioimmunoscintigraphy (RIS) was compared with computed tomography (CT) and operation in the primary diagnostic procedure and follow-up of women with suspected ovarian cancer. In primary diagnosis, sensitivity, specificity, and diagnostic accuracy was 100%, 60% and 90% for RIS. In follow-up, sensitivity for local recurrence was slightly higher in CT than in RIS. It was possible to detect peritoneal carcinosis in the pelvis and lower abdominal region better with RIS, but in the upper abdominal region, peritoneal carcinosis was detected better with CT. If no differentiation between benign or malignant lesion, is possible with CT, differentiation will in many cases be possible with RIS.

摘要

在这项前瞻性研究中,对疑似卵巢癌女性进行初步诊断和随访时,比较了放射免疫闪烁显像(RIS)与计算机断层扫描(CT)及手术的诊断价值。在初步诊断中,RIS的敏感性、特异性和诊断准确性分别为100%、60%和90%。在随访中,CT对局部复发的敏感性略高于RIS。RIS能更好地检测盆腔和下腹部区域的腹膜癌,但在上腹部区域,CT对腹膜癌的检测效果更好。如果CT无法区分良性或恶性病变,那么在许多情况下RIS有可能做到区分。

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Radioimmunoscintigraphy of ovarian tumours with technetium-99m labelled monoclonal antibody-170: first clinical experiences.用锝-99m标记单克隆抗体-170对卵巢肿瘤进行放射免疫闪烁显像:首次临床经验。
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