Barzen G, Cordes M, Langer M, Friedman W, Mayr A C, Felix R
Strahlenklinik mit Poliklinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.
Rofo. 1990 Jul;153(1):85-91. doi: 10.1055/s-2008-1033338.
In this prospective study the diagnostic merit of radioimmunoscintigraphy (RIS) was compared with computed tomography (CT) and operation in the primary diagnostic procedure and follow-up of women with suspected ovarian cancer. In primary diagnosis, sensitivity, specificity, and diagnostic accuracy was 100%, 60% and 90% for RIS. In follow-up, sensitivity for local recurrence was slightly higher in CT than in RIS. It was possible to detect peritoneal carcinosis in the pelvis and lower abdominal region better with RIS, but in the upper abdominal region, peritoneal carcinosis was detected better with CT. If no differentiation between benign or malignant lesion, is possible with CT, differentiation will in many cases be possible with RIS.
在这项前瞻性研究中,对疑似卵巢癌女性进行初步诊断和随访时,比较了放射免疫闪烁显像(RIS)与计算机断层扫描(CT)及手术的诊断价值。在初步诊断中,RIS的敏感性、特异性和诊断准确性分别为100%、60%和90%。在随访中,CT对局部复发的敏感性略高于RIS。RIS能更好地检测盆腔和下腹部区域的腹膜癌,但在上腹部区域,CT对腹膜癌的检测效果更好。如果CT无法区分良性或恶性病变,那么在许多情况下RIS有可能做到区分。