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[利用单克隆抗体免疫闪烁显像检测卵巢癌转移灶]

[The detection of metastases of ovarian carcinoma by immunoscintigraphy with monoclonal antibodies].

作者信息

Peking A, Marinov V

出版信息

Akush Ginekol (Sofiia). 1990;29(1):57-60.

PMID:2164792
Abstract

Sixty eight women, operated for ovarian carcinoma, were studied by monoclonal antibodies anti-CA-125 labeled with 131I. 99m-Tc was used for the scintigraphy. Ninety-one metastases were discovered as 73 of them were established surgically. 52/61 were confirmed in the pelvis, 19/24 in the abdominal cavity and 3/6 in the liver. Higher precision of immunoscintigraphy was found in the diagnosis of liver metastasis, when it was compared with echographic and computed tomographic examinations.

摘要

对68例接受卵巢癌手术的女性患者,采用131I标记的抗CA - 125单克隆抗体进行研究。使用99m - Tc进行闪烁扫描。共发现91处转移灶,其中73处经手术确诊。52/61处转移灶在盆腔得到证实,19/24处转移灶在腹腔,3/6处转移灶在肝脏。与超声和计算机断层扫描检查相比,免疫闪烁扫描在诊断肝转移时具有更高的准确性。

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