Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
J Neurosurg Spine. 2011 Sep;15(3):238-51. doi: 10.3171/2011.4.SPINE10543. Epub 2011 Jun 10.
The authors present a review of spinal cord blood supply, discussing the anatomy of the vascular system and physiological aspects of blood flow regulation in normal and injured spinal cords. Unique anatomical functional properties of vessels and blood supply determine the susceptibility of the spinal cord to damage, especially ischemia. Spinal cord injury (SCI), for example, complicating thoracoabdominal aortic aneurysm repair is associated with ischemic trauma. The rate of this devastating complication has been decreased significantly by instituting physiological methods of protection. Traumatic SCI causes complex changes in spinal cord blood flow, which are closely related to the severity of injury. Manipulating physiological parameters such as mean arterial blood pressure and intrathecal pressure may be beneficial for patients with an SCI. Studying the physiopathological processes of the spinal cord under vascular compromise remains challenging because of its central role in almost all of the body's hemodynamic and neurofunctional processes.
作者对脊髓的血液供应进行了综述，讨论了血管系统的解剖结构以及正常和损伤脊髓的血流调节的生理方面。血管和血液供应的独特解剖功能特性决定了脊髓对损伤，尤其是缺血的易感性。例如，胸主动脉瘤修复术后合并脊髓缺血性损伤的脊髓损伤（SCI）。通过实施生理保护方法，显著降低了这种灾难性并发症的发生率。创伤性 SCI 导致脊髓血流发生复杂变化，这与损伤的严重程度密切相关。操纵平均动脉血压和鞘内压等生理参数可能对 SCI 患者有益。由于脊髓在几乎所有身体的血液动力学和神经功能过程中都起着核心作用，因此研究血管受损时脊髓的病理生理过程仍然具有挑战性。
