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使用迭代重建降低鼻窦低剂量 CT 的辐射剂量:可行性和图像质量。

Reducing the radiation dose for low-dose CT of the paranasal sinuses using iterative reconstruction: feasibility and image quality.

机构信息

Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.

出版信息

Eur J Radiol. 2012 Sep;81(9):2246-50. doi: 10.1016/j.ejrad.2011.05.002. Epub 2011 Jun 12.

DOI:10.1016/j.ejrad.2011.05.002
PMID:21664084
Abstract

PURPOSE

To evaluate image quality of dose-reduced CT of the paranasal-sinus using an iterative reconstruction technique.

METHODS

In this study 80 patients (mean age: 46.9±18 years) underwent CT of the paranasalsinus (Siemens Definition, Forchheim, Germany), with either standard settings (A: 120 kV, 60 mAs) reconstructed with conventional filtered back projection (FBP) or with tube current-time product lowering of 20%, 40% and 60% (B: 48 mAs, C: 36 mAs and D: 24 mAs) using iterative reconstruction (n=20 each). Subjective image quality was independently assessed by four blinded observers using a semiquantitative five-point grading scale (1=poor, 5=excellent). Effective dose was calculated from the dose-length product. Mann-Whitney-U-test was used for statistical analysis.

RESULTS

Mean effective dose was 0.28±0.03 mSv(A), 0.23±0.02 mSv(B), 0.17±0.02 mSv(C) and 0.11±0.01 mSv(D) resulting in a maximum dose reduction of 60% with iterative reconstruction technique as compared to the standard low-dose CT. Best image quality was observed at 48 mAs (mean 4.8; p<0.05), whereas standard low-dose CT (A) and maximum dose reduced scans (D) showed no significant difference in subjective image quality (mean 4.37 (A) and 4.31 (B); p=0.72). Interobserver agreement was excellent (κ values 0.79-0.93).

CONCLUSION

As compared to filtered back projection, the iterative reconstruction technique allows for significant dose reduction of up to 60% for paranasal-sinus CT without impairing the diagnostic image quality.

摘要

目的

评估使用迭代重建技术降低鼻窦 CT 剂量的图像质量。

方法

本研究纳入 80 例患者(平均年龄:46.9±18 岁),行鼻窦 CT 检查(西门子 Definition,Forchheim,德国),分别采用标准设置(A:120kV,60mAs)和常规滤波反投影(FBP)重建、管电流时间乘积降低 20%、40%和 60%(B:48mAs、C:36mAs 和 D:24mAs)进行迭代重建(每组 20 例)。4 名观察者独立采用半定量 5 分制评估主观图像质量(1=差,5=优)。有效剂量根据剂量长度乘积计算。采用曼-惠特尼 U 检验进行统计学分析。

结果

A、B、C 和 D 组的平均有效剂量分别为 0.28±0.03mSv、0.23±0.02mSv、0.17±0.02mSv 和 0.11±0.01mSv,与标准低剂量 CT 相比,迭代重建技术的最大剂量降低 60%。48mAs 时图像质量最佳(平均 4.8;p<0.05),而标准低剂量 CT(A)和最大剂量降低扫描(D)的主观图像质量无显著差异(平均 4.37(A)和 4.31(B);p=0.72)。观察者间一致性极好(κ 值 0.79-0.93)。

结论

与滤波反投影相比,迭代重建技术可将鼻窦 CT 的剂量降低高达 60%,而不会降低诊断图像质量。

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