Fernández Fernández A, Maganto Pavón E, García González R, Vallejo Serrador J, Escudero Barrilero A
Servicios de Urología y Anatomia Patológica, del Hospital Ramón y Cajal, Madrid, España.
Arch Esp Urol. 1990 May;43(4):355-8.
Primary signet ring cell adenocarcinoma of the bladder is a very uncommon tumor type. Only 20 cases have been reported to date. Two additional cases are described. One patient was diagnosed as having plastic linitis of the bladder. The interval between the onset of symptoms and diagnosis ranged from 2-8 months. Tumor stage was P4 N4 MO and P4 N4 M1 at the time of diagnosis and survival was 3 and 1 month, respectively. This is a tumor with a remarkable intramural proliferation, in the advanced stages at the time of diagnosis, and a poor prognosis. To date, no widely-accepted therapeutic approach has been established.
原发性膀胱印戒细胞腺癌是一种非常罕见的肿瘤类型。迄今为止,仅报道过20例。本文描述另外2例。1例患者被诊断为膀胱浆膜下炎。症状出现至诊断的间隔时间为2至8个月。诊断时肿瘤分期分别为P4 N4 M0和P4 N4 M1,生存期分别为3个月和1个月。这是一种在诊断时已处于晚期、具有显著壁内增殖且预后较差的肿瘤。迄今为止,尚未确立广泛接受的治疗方法。