González Mínguez C, de Torres Ramírez I, Bosch Princep R, Idoipe Tomás J I
Departamento de Anatomía Patológica, Ciudad Sanitaria Vall d'Hebron, Barcelona, España.
Arch Esp Urol. 1996 Jun;49(5):517-20.
Two additional cases of signet-ring cell adenocarcinoma of the urinary bladder, an uncommon highly malignant tumor type, are described.
METHODS/RESULTS: The clinical features, histopathological findings and immunohistochemical study are presented.
Both cases previously had cystic glandular cystitis, which supports the totipotent urothelium origin of this neoplasm. Signet-ring cell adenocarcinoma or linitis plastica of the bladder has a highly malignant course despite neoadjuvant chemotherapy and total cystectomy.
描述另外两例膀胱印戒细胞腺癌,这是一种罕见的高恶性肿瘤类型。
方法/结果:介绍了临床特征、组织病理学发现及免疫组化研究。
两例病例之前均有囊性腺性膀胱炎,这支持了该肿瘤的全能尿路上皮起源。尽管进行了新辅助化疗和全膀胱切除术,但膀胱印戒细胞腺癌或皮革胃仍有高度恶性的病程。