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骨关节炎。

Osteoarthritis.

机构信息

Population Health and Macular Research Units, Centre for Eye Research Australia, University of Melbourne, Carlton, Victoria, Australia.

出版信息

Best Pract Res Clin Rheumatol. 2010 Dec;24(6):757-68. doi: 10.1016/j.berh.2010.11.001.

Abstract

Internationally, prevalence estimates for osteoarthritis show wide variability depending on the age and sex of the studied population, the method of case identification used, and the specificity of joint sites included. Currently, there is no generally agreed "gold standard" for identifying cases of osteoarthritis in epidemiologic studies. Despite this lack of standardisation, it is consistently demonstrated in population-based studies, worldwide, that osteoarthritis prevalence is positively associated with increasing age and that the greatest disease burden is attributable to involvement of the hip or knee joints. To estimate the true burden of osteoarthritis involving the hips or knees, comprehensive accounting of all associated morbidity is required. The identification of modifiable risk factors for disease incidence and progression is needed.

摘要

在国际上,骨关节炎的患病率估计值因研究人群的年龄和性别、所使用的病例识别方法以及所包含的关节部位的特异性而有很大差异。目前,在流行病学研究中,还没有普遍认可的确定骨关节炎病例的“金标准”。尽管缺乏标准化,但在全球范围内的基于人群的研究中一致表明,骨关节炎的患病率与年龄的增长呈正相关,并且最大的疾病负担归因于髋关节或膝关节受累。为了估计涉及髋关节或膝关节的骨关节炎的真实负担,需要全面考虑所有相关的发病率。需要确定疾病发病和进展的可改变风险因素。

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