Tafti Saeid Fallah, Cheraghvandi Ali, Mokri Bahareh, Talischi Firouzeh
Department of Pulmonary Medicine, Masih Daneshvari Hospital, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Dar Abad, Tehran, Islamic Republic of Iran.
J Asthma. 2011 Aug;48(6):589-92. doi: 10.3109/02770903.2011.587578. Epub 2011 Jun 13.
The Saint George Respiratory Questionnaire (SGRQ) is a well-known questionnaire for evaluating the quality of life in asthmatic patients. It has been translated to Persian and its validity and specificity should be evaluated for chronic obstructive pulmonary disease patients. In this study, we attempted to improve the questionnaire's adaptability to Persian culture and also evaluate its validity, specificity, and applicability among asthmatics at our tertiary referral center.
Previously translated and psychometrically evaluated SGRQ for chronic obstructive pulmonary disease patients was made more adaptive to Persian. Upon acceptability of the questionnaire by a small group of patients, 301 asthmatics referred for spirometry and completed the form. Consistency was evaluated using Cronbach's α coefficient and validity was assessed by comparison of scores with other measures of asthma exacerbation. These measures included FEV1, patient's clinical presentation, visual analog scale (used to assess difficulty breathing), Katz activity index and section scores of the General Health Questionnaire, anxiety, depression, and social impact.
The study group included 165 female and 139 male asthmatics with a mean age of 44.4 ± 1.0 years. Measurement of consistency for the SGRQ revealed Cronbach's α to be 0.699 for symptoms, 0.805 for activity, 0.879 for impact, and 0.916 for the total questionnaire. By omitting question 8, time of wheezing during the day increased Cronbach's coefficient of the symptoms section to 0.719. Omitting "uselessness of respiratory drugs" from the impact section increased Cronbach's α to 0.881. However, scoring of the section then varied from the original questionnaire. A statistically significant correlation was found between the SGRQ sections and total score (using Katz index and General Health Questionnaire, p < .001).
Our study showed good validity and reliability for the Persian version of SGRQ for a population of asthmatics referred to our tertiary pulmonary clinic.
圣乔治呼吸问卷（SGRQ）是一种用于评估哮喘患者生活质量的知名问卷。该问卷已被翻译成波斯语，其有效性和特异性应针对慢性阻塞性肺疾病患者进行评估。在本研究中，我们试图提高该问卷对波斯文化的适应性，并评估其在我们的三级转诊中心哮喘患者中的有效性、特异性和适用性。
之前针对慢性阻塞性肺疾病患者翻译并进行心理测量评估的SGRQ，使其更适应波斯语。在一小群患者接受该问卷后，301名因肺功能测定前来就诊的哮喘患者填写了表格。使用克朗巴哈α系数评估一致性，并通过将分数与其他哮喘加重指标进行比较来评估有效性。这些指标包括第一秒用力呼气容积（FEV1）、患者的临床表现、视觉模拟量表（用于评估呼吸困难程度）、卡茨活动指数以及一般健康问卷的各部分得分、焦虑、抑郁和社会影响。
研究组包括165名女性和139名男性哮喘患者，平均年龄为44.4±1.0岁。SGRQ一致性测量显示，症状部分的克朗巴哈α系数为0.699，活动部分为0.805，影响部分为0.879，整个问卷为0.916。通过省略问题8（白天喘息时间），症状部分的克朗巴哈系数提高到0.719。从影响部分省略“呼吸药物无用”后，克朗巴哈α系数提高到0.881。然而，该部分的评分随后与原始问卷不同。SGRQ各部分与总分之间存在统计学显著相关性（使用卡茨指数和一般健康问卷，p<0.001）。
我们的研究表明，对于转诊至我们三级肺病诊所的哮喘患者群体，波斯语版SGRQ具有良好的有效性和可靠性。
