Kitamura Akira, Yamashita Hiromi, Okumura Teruhito, Asahina Izumi
Division of Oral and Maxillofacial Surgical Reconstruction and Functional Restoration, Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jul;112(1):e1-3. doi: 10.1016/j.tripleo.2011.03.009.
Congenital factor V deficiency was first described by Owren in 1947.(1) It is thought to be transmitted by an autosomal recessive gene (q23-24)(2) found in 1 out of every 1 million population and usually with no gender or race correlation.(3) To date, ~150 cases have been reported in the world literature.(3) The description of rare case of this disease is justified, because they may add further information about the condition of the hemorrhagic tendency. The object of the present paper was to report the bleeding control for extraction of 4 wisdom teeth with congenital factor V deficiency hemophilia and review the literature.
先天性因子V缺乏症于1947年由奥伦首次描述。（1）它被认为是由常染色体隐性基因（q23 - 24）（2）传递的，在每100万人口中就有1例，通常与性别或种族无关。（3）迄今为止，世界文献中已报道了约150例。（3）对这种罕见疾病病例进行描述是合理的，因为它们可能会为出血倾向状况增添更多信息。本文的目的是报告对4例患有先天性因子V缺乏血友病患者拔除智齿时的出血控制情况并回顾相关文献。
