School of Population Health, University of Queensland, Brisbane, Australia.
J Neurol Sci. 2011 Sep 15;308(1-2):135-8. doi: 10.1016/j.jns.2011.05.016. Epub 2011 Jun 13.
Hypertension and the prevalence of stroke are increasing in the Middle East and North Africa. This study aims to quantify the contribution of hypertension to the development of stroke at the country-level by calculating the sex-specific population attributable fraction (PAFs).
The most recent sex-specific prevalence data was used, along with age-adjusted hazard ratio (HR) estimates for ischemic and hemorrhagic stroke associated with hypertension from the Asia Pacific Cohort Studies Collaboration (APCSC). HR estimates and prevalence data were then used to calculate the PAFs for each country in the region with the relevant data.
In the 10 countries with nationally-representative data, the PAFs in men ranged from 16.3% in Kuwait to 60.7% in Morocco for hemorrhagic stroke and 7.2% in Kuwait to 38% in Morocco for ischemic stroke. The equivalent PAFs for stroke deaths related to hypertension in women ranged from 12.4% in United Arab Emirates to 48.6% in Bahrain for hemorrhagic stroke and from 10.3% in UAE to 46% in Morocco for ischemic stroke.
Overall, up to 60% of stroke can be attributed to the high blood pressure in the Middle East. Stroke is a preventative disease, with this information and better prevention strategies, this region can aim to lower the prevalence of stroke.
高血压和中风的患病率在中东和北非地区不断上升。本研究旨在通过计算特定性别人群归因分数（PAF）来量化高血压对该地区国家一级中风发病的影响。
使用了最新的特定性别患病率数据，以及亚太队列研究协作组织（APCSC）关于高血压与缺血性和出血性中风相关的年龄调整后的危险比（HR）估计值。然后，使用这些 HR 估计值和患病率数据，计算了该地区具有相关数据的每个国家的 PAF。
在 10 个具有全国代表性数据的国家中，男性中与出血性中风相关的 PAF 范围从科威特的 16.3%到摩洛哥的 60.7%，与缺血性中风相关的 PAF 范围从科威特的 7.2%到摩洛哥的 38%。与高血压相关的女性中风死亡的 PAF 范围从阿联酋的 12.4%到巴林的 48.6%，与缺血性中风相关的 PAF 范围从阿联酋的 10.3%到摩洛哥的 46%。
总的来说，高达 60%的中风可以归因于该地区的高血压。中风是一种可预防的疾病，有了这些信息和更好的预防策略，该地区可以努力降低中风的发病率。
