Institute of Biochemistry, Eidgenössische Technische Hochschule Zürich, 8093 Zürich, Switzerland.
J Cell Biol. 2011 Jun 13;193(6):959-61. doi: 10.1083/jcb.201105076.
Septins form a filamentous collar at the mother-bud neck in budding yeast. In cytokinesis, this collar splits into two rings and the septin complexes undergo a dramatic reorientation. Using fluorescence polarization microscopy, DeMay et al. (2011. J. Cell Biol. doi:10.1083/jcb.201012143) now demonstrate that septin complexes assemble as paired filaments in vivo and reveal new insights into septin organization during cytokinesis.
在出芽酵母中，Septins 形成母-芽颈部的丝状领环。在胞质分裂过程中，该领环分裂成两个环，并且 septin 复合物发生剧烈重定向。DeMay 等人（2011. J. Cell Biol. doi:10.1083/jcb.201012143）现在使用荧光偏振显微镜证明 septin 复合物在体内作为成对的细丝组装，并揭示了胞质分裂过程中 septin 组织的新见解。
