Shazly Tarek A, Latina Mark A
Department of Ophthalmology, Assiut University Hospital, Assiut, Egypt.
Arch Ophthalmol. 2011 Jun;129(6):699-702. doi: 10.1001/archophthalmol.2011.108.
To determine if the intraocular pressure (IOP) response to selective laser trabeculoplasty (SLT) in one eye predicts long-term response to SLT in the fellow eye.
A retrospective medical record review was performed of patients who underwent SLT as primary treatment in both eyes and who completed at least 30 months of follow-up visits. Pearson product moment correlation analysis was performed to determine correlations between the 3-month percentage of IOP reduction in the first treated eye and long-term percentages of IOP reduction in the fellow eye.
Medical records of 80 eyes in 40 patients were reviewed. In patients with ocular hypertension, the 3-month percentage of IOP reduction in the first treated eye correlated strongly with long-term percentages of IOP reduction in the fellow eye (r > 0.652). In patients with primary open-angle glaucoma, the 3-month percentage of IOP reduction in the first treated eye correlated moderately with percentages of IOP reduction in the fellow eye up to 9 months (r > 0.367).
In patients with ocular hypertension, the 3-month percentage of IOP reduction in the first treated eye in response to SLT was predictive of response in the fellow eye up to 30 months. In patients with primary open-angle glaucoma, the 3-month percentage of IOP reduction in the first treated eye in response to SLT was predictive of response in the fellow eye up to 9 months.
确定单眼选择性激光小梁成形术（SLT）后的眼压（IOP）反应能否预测对侧眼SLT的长期反应。
对双眼均接受SLT作为初始治疗且完成至少30个月随访的患者进行回顾性病历审查。采用Pearson积差相关分析来确定首次治疗眼3个月时眼压降低百分比与对侧眼长期眼压降低百分比之间的相关性。
对40例患者的80只眼的病历进行了审查。在高眼压患者中，首次治疗眼3个月时眼压降低百分比与对侧眼长期眼压降低百分比密切相关（r>0.652）。在原发性开角型青光眼患者中，首次治疗眼3个月时眼压降低百分比与对侧眼长达9个月时的眼压降低百分比中度相关（r>0.367）。
在高眼压患者中，首次治疗眼对SLT反应的3个月眼压降低百分比可预测对侧眼长达30个月的反应。在原发性开角型青光眼患者中，首次治疗眼对SLT反应的3个月眼压降低百分比可预测对侧眼长达9个月的反应。
