Viana Giovanni André Pires, Osaki Midori Hentona, Cariello Angelino Júlio, Damasceno Renato Wendell
Serviço de Plástica Ocular, Instituto da Visão, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Arq Bras Oftalmol. 2011 Jan-Feb;74(1):44-7. doi: 10.1590/s0004-27492011000100010.
Volume loss and muscular hyperactivity are two major components of the aging process that contribute to the formation of the folds and wrinkles. Tear trough deformity is one of the most difficult depressions to correct surgically.
The aim of this study was to evaluate the results of ten patients submitted to periorbital filling with hyaluronic acid gel filler.
Between June and August, 2008, 10 patients have had their tears troughs treated with hyaluronic acid gel filler. The filler was introduced by a serial puncture technique and approximately 0.1 ml was injected at each pass. The filler was placed in the pre-periosteal tissue. Patients photographs before and after the procedure were reviewed to assess the outcomes.
The mean volume per side needed to achieve correction was on the right side 0.61 ml (SD=0.25) and on the left side 0.65 ml (SD=0.26). The most common complications were bruising, erythema, local swelling, and pain at the injection site. The effect of treatment lasted up to 12 months.
This pilot study showed that the treatment of tear trough deformity with hyaluronic acid gel filler was feasible, predictable and effective. All patients were very satisfied with their results.
容量减少和肌肉活动亢进是衰老过程中的两个主要因素，它们促使皱纹的形成。泪沟畸形是手术矫正最困难的凹陷之一。
本研究旨在评估10例接受透明质酸凝胶填充剂眶周填充患者的治疗效果。
2008年6月至8月期间，10例患者接受了透明质酸凝胶填充剂治疗泪沟。采用连续穿刺技术注入填充剂，每次注入约0.1ml。填充剂置于骨膜前组织。回顾患者手术前后的照片以评估治疗效果。
右侧达到矫正所需的平均每侧容量为0.61ml（标准差=0.25），左侧为0.65ml（标准差=0.26）。最常见的并发症是注射部位出现瘀斑、红斑、局部肿胀和疼痛。治疗效果持续长达12个月。
这项初步研究表明，用透明质酸凝胶填充剂治疗泪沟畸形是可行、可预测且有效的。所有患者对其治疗效果都非常满意。
