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Which is the most effective strategy: early detection of coagulopathy with thromboelastometry or use of hemostatic factors or both?哪种策略最有效：通过血栓弹力图早期检测凝血病，还是使用止血因子，抑或是两者兼用？
Crit Care. 2011;15(3):433; author reply 433. doi: 10.1186/cc10224. Epub 2011 Jun 13.
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Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy.创伤输血：血栓弹力图引导的凝血因子浓缩物治疗与标准新鲜冷冻血浆治疗的比较。
Crit Care. 2011;15(2):R83. doi: 10.1186/cc10078. Epub 2011 Mar 4.
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A comparative study of viscoelastic hemostatic assays and conventional coagulation tests in trauma patients receiving fibrinogen concentrate.纤维蛋白原浓缩物治疗创伤患者中黏弹性止血检测与常规凝血检测的比较研究。
Clin Chim Acta. 2019 Aug;495:253-262. doi: 10.1016/j.cca.2019.04.066. Epub 2019 Apr 17.
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Rotational thromboelastometry and its use in directing the management of coagulopathy in the battle injured trauma patient.
J Perioper Pract. 2014 Jan-Feb;24(1-2):25-8. doi: 10.1177/1750458916024001-205.
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Fibrinogen in trauma, an evaluation of thrombelastography and rotational thromboelastometry fibrinogen assays.创伤中的纤维蛋白原：血栓弹力图和旋转血栓弹力测定法纤维蛋白原检测的评估
J Surg Res. 2015 Apr;194(2):581-590. doi: 10.1016/j.jss.2014.11.021. Epub 2014 Nov 20.
6
Rotational thromboelastometry significantly optimizes transfusion practices for damage control resuscitation in combat casualties.旋转血栓弹力图显著优化了战斗伤员损伤控制复苏的输血方案。
J Trauma Acute Care Surg. 2017 Sep;83(3):373-380. doi: 10.1097/TA.0000000000001568.
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The impact of early thromboelastography directed therapy in trauma resuscitation.早期血栓弹力描记术指导治疗在创伤复苏中的影响。
Scand J Trauma Resusc Emerg Med. 2017 Oct 5;25(1):99. doi: 10.1186/s13049-017-0443-4.
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A systematic review on the rotational thrombelastometry (ROTEM®) values for the diagnosis of coagulopathy, prediction and guidance of blood transfusion and prediction of mortality in trauma patients.关于旋转血栓弹力图（ROTEM®）值在创伤患者凝血病诊断、输血预测与指导及死亡率预测方面的系统评价。
Scand J Trauma Resusc Emerg Med. 2016 Oct 3;24(1):114. doi: 10.1186/s13049-016-0308-2.
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Thromboelastography and Thromboelastometry in Assessment of Fibrinogen Deficiency and Prediction for Transfusion Requirement: A Descriptive Review.血栓弹力描记术和血栓弹力测量术在评估纤维蛋白原缺乏症和预测输血需求中的应用：描述性综述。
Biomed Res Int. 2018 Nov 25;2018:7020539. doi: 10.1155/2018/7020539. eCollection 2018.
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Rotational thromboelastometry thresholds for patients at risk for massive transfusion.大量输血风险患者的旋转血栓弹力图阈值
J Surg Res. 2018 Aug;228:154-159. doi: 10.1016/j.jss.2018.03.027. Epub 2018 Apr 11.

引用本文的文献

1
Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding.用于成年创伤出血患者创伤性凝血病的血栓弹力图（TEG）和旋转血栓弹力测定法（ROTEM）
Cochrane Database Syst Rev. 2015 Feb 16;2015(2):CD010438. doi: 10.1002/14651858.CD010438.pub2.
2
Hemorrhagic shock: The "physiology approach".失血性休克：“生理学方法”
J Emerg Trauma Shock. 2012 Oct;5(4):285-95. doi: 10.4103/0974-2700.102357.

本文引用的文献

1
Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy.创伤输血：血栓弹力图引导的凝血因子浓缩物治疗与标准新鲜冷冻血浆治疗的比较。
Crit Care. 2011;15(2):R83. doi: 10.1186/cc10078. Epub 2011 Mar 4.
2
Relative concentrations of haemostatic factors and cytokines in solvent/detergent-treated and fresh-frozen plasma.溶剂/去污处理血浆和新鲜冷冻血浆中止血因子和细胞因子的相对浓度。
Br J Anaesth. 2011 Apr;106(4):505-11. doi: 10.1093/bja/aer003. Epub 2011 Feb 9.
3
Management of bleeding following major trauma: an updated European guideline.严重创伤后出血的处理：欧洲最新指南。
Crit Care. 2010;14(2):R52. doi: 10.1186/cc8943. Epub 2010 Apr 6.
4
Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations.纤维蛋白原浓缩物替代疗法用于大出血且血浆纤维蛋白原浓度低的患者。
Br J Anaesth. 2008 Dec;101(6):769-73. doi: 10.1093/bja/aen270. Epub 2008 Sep 25.
5
Prothrombin complex concentrate (Beriplex P/N) in severe bleeding: experience in a large tertiary hospital.凝血酶原复合物浓缩剂（百瑞凝P/N）用于严重出血：一家大型三级医院的经验
Crit Care. 2008;12(4):R105. doi: 10.1186/cc6987. Epub 2008 Aug 15.
6
The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital.在一家军队战斗支援医院接受大量输血的伤员中，输注的纤维蛋白原与红细胞的比例会影响其存活率。
J Trauma. 2008 Feb;64(2 Suppl):S79-85; discussion S85. doi: 10.1097/TA.0b013e318160a57b.

Which is the most effective strategy: early detection of coagulopathy with thromboelastometry or use of hemostatic factors or both?

作者信息

David Jean-Stephane, Marchal Virginie, Levrat Albrice, Inaba Kenji

出版信息

Crit Care. 2011;15(3):433; author reply 433. doi: 10.1186/cc10224. Epub 2011 Jun 13.

DOI:10.1186/cc10224
PMID:21672283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3218978/
Abstract
摘要