Wier Lauren M, Hatcher Mary S, Triche Elizabeth W, Lo Albert C
Department of Community Health, Brown University, Providence, RI, USA.
J Rehabil Res Dev. 2011;48(4):483-92. doi: 10.1682/jrrd.2010.03.0035.
This study describes the effect of body-weight-supported treadmill training (BWSTT) on quality of life (QoL) for multiple sclerosis (MS) patients. Thirteen individuals with MS and gait impairment randomly received two blocks of six biweekly training sessions: (1) robot-assisted BWSTT then BWSTT alone (R-T) or (2) BWSTT alone then robot-assisted BWSTT (T-R). No statistically significant differences were found between robot-assisted BWSTT and unassisted BWSTT for improving QoL outcome measures. The change in Physical Component Summary scores from baseline to the end of the 12 training sessions improved significantly more in the R-T than the T-R group. Within-participant longitudinal changes in QoL for all participants from both groups combined showed significant improvements in 5 of the 13 QoL measures. The results of this pilot study suggest that both types of BWSTT may improve QoL for people with gait dysfunction secondary to MS.
本研究描述了体重支持跑步机训练（BWSTT）对多发性硬化症（MS）患者生活质量（QoL）的影响。13名患有MS且有步态障碍的个体随机接受两个阶段，每个阶段包含六个每两周进行一次的训练课程：（1）先进行机器人辅助的BWSTT，然后单独进行BWSTT（R-T），或（2）先单独进行BWSTT，然后进行机器人辅助的BWSTT（T-R）。在改善生活质量结果指标方面，机器人辅助的BWSTT与非辅助的BWSTT之间未发现统计学上的显著差异。从基线到12次训练结束时，R-T组的身体成分总结得分变化比T-R组有更显著的改善。两组所有参与者的生活质量的参与者内纵向变化显示，13项生活质量指标中有5项有显著改善。这项初步研究的结果表明，两种类型的BWSTT都可能改善继发于MS的步态功能障碍患者的生活质量。
